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Scientists Gave a Bunch of Salmon Cocaine. This Is What Happened Next.

2026-04-21 03:40:33

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Scientists Gave a Bunch of Salmon Cocaine. This Is What Happened Next.

Salmon exposed to cocaine swim farther and behave differently than unexposed fish, according to the first study to observe the effects of cocaine on fish in the wild rather than a laboratory setting.

Many waterways around the world are contaminated with a host of legal and illegal substances that are consumed by humans and then excreted into sewage systems. As global demand for cocaine skyrockets, traces of the drug—including its main metabolite, benzoylecgonine—are flowing into lakes and rivers where they can be absorbed by wildlife, such as Atlantic salmon.

Previous research in laboratory conditions has already linked cocaine exposure to behavioral changes in aquatic species, but this connection has never been explored in fish in the wild. Now, scientists have demonstrated that cocaine and benzoylecgonine “can accumulate in the brains of exposed Atlantic salmon—an ecologically and economically important species of high conservation concern—and disrupt the movement and space use of these fish in the wild,” according to a study published on Monday in Current Biology.

“We were motivated by a major gap in the scientific literature: almost everything that was known about the impacts of cocaine pollution on animal behaviour relies on data that has been collected in laboratory settings,” said Michael Bertram, an author of the study and an associate professor in the department of wildlife, fish, and environmental studies at the Swedish University of Agricultural Sciences, in an email to 404 Media. 

“We wanted to know whether environmentally realistic exposure to cocaine and its major metabolite, benzoylecgonine, actually changes how fish move in the wild under real ecological and environmental conditions,” he continued.

To fill this knowledge gap, Bertram and his colleagues obtained more than a hundred Atlantic salmon “smolts”—the term for young fish—that were raised in a hatchery until they were two years old. The team divided them into three groups of 35 fish each and equipped every fish with an implant and tracking tags. The “cocaine group” received a slow-release chemical implant of cocaine, the “metabolite group” received a slow-release benzoylecgonine implant, and a third “control group” carried a dummy implant with no chemicals.  

Scientists Gave a Bunch of Salmon Cocaine. This Is What Happened Next.
Graphical abstract outlining the team’s approach. Image: Brand, Jack et al. 

The three groups were released simultaneously on April 12, 2022 at the same site on the south-western side of Lake Vättern in Sweden, alongside 200 other smolts that were not involved in this experiment. Over the course of roughly two months, the exposed groups moved much more than the control group, especially the metabolite group; they traveled 1.9 times farther per week than the unexposed smolts.

“We expected an effect of contaminant exposure on the movement of salmon, but the scale of the changes seen still surprised us,” Bertram said. “The strongest response was close to a two-fold increase in movement, and the most unexpected result was that benzoylecgonine, the main metabolite of cocaine, produced the clearest effect rather than cocaine itself.”

Indeed, the study found that the metabolite group swam almost nine miles farther per week than the control week in the final two weeks of the 8-week experiment, whereas the control group was more settled down by that point.

“To the best of our knowledge, this is the first demonstration that environmental levels of a cocaine metabolite that is commonly found in aquatic ecosystems can alter the space use and swimming activity of fish in the wild,” the team said in the study. 

It’s not clear why the metabolite group was so restless, given that benzoylecgonine is considered psychoactively inactive in humans. The compound is a long-lived byproduct of cocaine made by the liver and excreted in urine, which makes it the easiest biomarker to look for in a typical drug test. The possibility that this metabolite may have a greater impact on some species in the wild is disturbing, in part because it is frequently found in higher concentrations in natural environments than its parent compound (cocaine).

“The results suggest that benzoylecgonine may be more biologically important than it is often assumed to be,” Bertram said. “Our findings raise new questions about whether metabolites can sometimes be as disruptive as, or even more disruptive than, the parent compound in aquatic wildlife.”

The team emphasized that much more research is required to understand the pressures that cocaine and other substances might be introducing both to individual species and to whole ecosystems. 

“The next steps are to work out the mechanisms by which cocaine and its metabolite disrupt behaviour and movement in fish in the wild, test how general this effect is across other species and systems, and use higher-resolution tracking to see whether these movement changes affect predation risk, migration, reproduction, or survival,” Bertram said. “That is really the key question now: not just whether behaviour changes, but what those changes mean ecologically.”

For example, this particular study focused on hatchery-raised smolts that were released into the wild, but future studies could test out the effects of these contaminants on fully wild populations as well, which have their own unique behavioral characteristics. Unraveling the effects of these human-sourced substances is even more urgent given that the global use of illicit drugs increased by roughly 20 percent over the last decade, suggesting that “the environmental impact of these substances is likely to grow,” according to the study.

“The behaviour and movement of wildlife underpin habitat use, feeding, predator exposure, and population connectivity, so altering these processes could have wider consequences for food webs and population dynamics,” Bertram concluded. “For species already under pressure, an added stressor like this could be highly detrimental, although the long-term effects on fisheries and ecosystems still need to be tested directly.”

Forbes Prediction Market Gamifies Story About Mass Shooting of 8 Children

2026-04-21 00:18:26

Forbes Prediction Market Gamifies Story About Mass Shooting of 8 Children

In another sign that the depravity economy has no bottom, Forbes published a story about a Louisiana man that killed 8 children over the weekend containing a box that asked readers to predict whether Congress would do anything about gun control. Citation Needed author Molly White first spotted the box and shared it on Bluesky.

Forbes Prediction Market Gamifies Story About Mass Shooting of 8 Children
Forbes.com screenshot.

On Sunday morning 31-year old Shamar Elkins killed eight children ages one to fourteen, including seven of his own kids, in a rampage across three locations in Shreveport, Louisiana. Police shot Elkins to death. The Forbes story summarized these events, aggregated the Associated Press and New York Times stories about the killings, and then asked readers to predict whether or not Congress will pass stricter gun laws.

“The New York Times reported his family members said he had mental health problems and had expressed suicidal thoughts,” Forbes said. And then, below that, a “ForbesPredict” box:

“Congress WILL/ WON’T pass new gun safety legislation before 31st December 2026?” The box said then asked readers to “make your prediction.” A green checkmark and red X pulsed in place. Sliding your cursor over each changes the construction of the sentence.

Forbes launched ForbesPredict in January as part of an effort to reverse declining traffic from search engines and keep users on its website longer. It’s a prediction market like Kalshi or Polymarket, but unlike those sites there’s no money to be won. “AI is fundamentally changing how people access information, and that shift is already starkly visible in publisher's traffic,” Nina Gould, Forbes’ Chief Innovation Officer said in a press release announcing ForbesPredict. “Our response isn’t to chase scale, but to deepen engagement. ForbesPredict gives our audience a reason to return, participate and invest their thinking—not just consume headlines.”

ForbesPredict is an attempt to gamify news consumption and keep users scanning the website. Rather than cash, players earn tokens. “Tokens that have no cash value but matter within the ForbesPredict ecosystem as a signal of judgment over time. The tokens unlock greater status, gameplay advantages, and non-monetary rewards along the way,” Gould told Publishing Insider in an interview about the launch of ForbesPredict.

As a new user who had not signed into Forbes.com, I had 800 tokens. A story about the horrifying murder of children in Louisiana invited me to predict the legislative future of gun control. It cost 100 tokens for me to predict that Congress will pass new gun laws by the end of 2026, an outcome ForbesPredict gave an 18 percent chance of happening. 

Forbes Prediction Market Gamifies Story About Mass Shooting of 8 Children
Forbes.com screenshot.

For 10 tokens I could get a “hint” about potential outcomes before spending 100 to make a prediction. The next question asked if Trump would pardon Ghislaine Maxwell before the end of his term. Paying 10 tokens for the hint revealed that ForbesPredict users say there’s a 61 percent chance Trump WILL pardon Maxwell. According to the hints this is because Trump said he’s allowed to do it. There’s a daily login bonus of 800 tokens for anyone willing to make an account.

Websites like Polymarket and Kalshi  allow people to bet on the outcomes of world events including of war and death. ForbesPredict is an ersatz version of Polymarket where no money changes hands and users spend tokens for clout internally on Forbes. It’s hard for me to picture the person who is interested in prediction markets without real money visiting Forbes daily to read watered down reporting from the Associated Press and New York Times and then clicking a little boxy like they’re playing Candy Crush with the news cycle.

Forbes built ForbesPredict in partnership with a company called Axiom. It’s an attempt to solve the very real problem of AI devouring traffic and referrals. “AI platforms are answering the questions your journalism used to answer, permanently restructuring how information flows,” Axiom’s website said. “The quiet hope that this was a fluke. The data says otherwise. The trajectory is clear.”

The trajectory is, indeed, clear. AI does seem to be restructuring how information flows on the internet. Forbes is making a bet that it can keep its digital business afloat by serving as a low-stakes prediction market for news junkies. It’s offering gambling without the stakes and the payout and it’s offering news without first hand reporting or new information. It remains to be seen if this will help it retain readers and keep people on the site.

Forbes did not return 404 Media’s request for a comment.

Why Journalists Are Going Indie (with Maddy Myers)

2026-04-20 21:00:27

Why Journalists Are Going Indie (with Maddy Myers)

This week, Sam is joined by Maddy Myers, editor-in-chief of Mothership. She’s also a co-host of the video games podcast Triple Click

Maddy launched Mothership with co-founder Zoë Hannah in January. It’s a queer and women-owned independent publication that focuses on gender and games. They discuss Maddy’s early days of games journalism at a (print!) alt-weekly in Boston and then at the Mary Sue, how she and Zoë decided it was time to quit their jobs and launch their own indie outlet, and the importance of owning your own work as a journalist.

Listen to the weekly podcast on Apple Podcasts, Spotify, or YouTube. Become a paid subscriber for access to this episode's bonus content and to power our journalism.

If you become a paid subscriber, check your inbox for an email from our podcast host Transistor for a link to the subscribers-only version! You can also add that subscribers feed to your podcast app of choice and never miss an episode that way. The email should also contain the subscribers-only unlisted YouTube link for the extended video version too. It will also be in the show notes in your podcast player.

Subscribe to Mothership

Why I’m launching a feminist video games website in 2026 - The Guardian

Mothership and a History of Women in Games Media - the Post Games podcast

Babies Born from Dead Parents Will Increase with New Tech. Are We Ready?

2026-04-18 21:00:34

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Subscribe to 404 Media to get The Abstract, our newsletter about the most exciting and mind-boggling science news and studies of the week.
Babies Born from Dead Parents Will Increase with New Tech. Are We Ready?

Welcome back to the Abstract! These are the studies this week that peacefully passed the crown, predicted trouble on the horizon, gave life after death, and coastally shelved an idea.

First, scientists watch a succession story play out for years in a naked mole rat colony. Then: prediction markets as a public health threat, the thorny questions of posthumous reproduction, and a walk on the shores of an ancient alien seas.

As always, for more of my work, check out my book First Contact: The Story of Our Obsession with Aliens or subscribe to my personal newsletter the BeX Files.

Digging into the palace intrigue of a rodent realm 

Abeywardena, Shanes C., M. Schraibman, Alexandria et al. “Peaceful queen succession in the naked mole rat.” Science Advances.

Murderous queens. Bloody power struggles. Strictly enforced hierarchies. I’m speaking, of course, of naked mole rats, a bizarre species of rodent that becomes embroiled in violent conflicts over the succession of one breeding queen to the next. 

Though aggression in succession is the norm for these animals, scientists now report a rare peaceful transition of power from one queen to her daughter in a captive colony. 

The discovery suggests that “the less common peaceful trajectory to queen succession…is possible under some conditions” especially when “aggression-based enforcement may be insufficient or unnecessary and when the cost of a ‘war’ may be too high,” according to the new study.

As we’ve covered before on the Abstract, mole rats (both the naked kind and the non-naked kind) are the only mammals to live in eusocial colonies similar to bees or ants, meaning they are reigned over by one breeding queen and her subordinate workers. In addition to this unique social structure, mole rats display a number of fascinating behavioral and genetic adaptations, including long lifespans and low rates of cancer, which has made them a popular species for research.

Naked mole rats may not look all that intimidating, but when it’s time to anoint a new queen, the fur starts to fly (or it would, if these animals had any fur). If a queen dies or is deposed by rivals, subordinate females in the colony battle to take the throne.

But scientists co-led by Shanes Abeywardena and Alexandria M. Schraibman of the Salk Institute for Biological Studies observed a different succession story that unfolded over many years in the Amigos captive colony housed in San Diego. 

Starting in 2019, a queen named Teré reigned over the colony and produced many healthy pups. Once the colony became crowded, with nearly 40 members, Queen Teré began delivering litters with no surviving pups. When the researchers removed half of the members, she began to produce surviving pups again, though not many. The team then deliberately introduced another stressor by moving the colony to a new facility in 2022, which ceased Queen Teré’s fertility.

Babies Born from Dead Parents Will Increase with New Tech. Are We Ready?
Summary of the Amigos colony’s succession story. Image: Abeywardena, Shanes C., M. Schraibman, Alexandria et al.

In response, Alexandria, one of Teré’s daughters, became pregnant in 2023 and 2024, but her litters also produced no survivors, and she had to be euthanized in 2024 due to a uterine torsion. Finally, the long reproductive hiatus was ended after three years by the ascension of Alexandria’s sister, Arwen, who became Queen Arwen upon her delivery of healthy pups in October 2025.

“Aside from a single incident on 6 February 2025 in which one animal was found with a superficial bite wound and dried blood around the face, an injury that resolved without recurrence, no aggression or dominance related conflict was observed,” the researchers said. “Instead, Queen Teré was reported to exhibit ‘guarding’ behavior of Arwen and her litter. No other signs of social instability, behavioral escalation, or colony-wide distress were documented.”

“Together, these observations indicate that following the decline of Queen Teré’s reproductive capacity and the loss of the intermediary breeder Alexandria, Arwen successfully assumed the reproductive role without eliciting aggression from the reigning queen or from other colony members,” the team concluded.

The study is an antidote to the story we covered last week about a lethal chimp “civil war,” demonstrating that animals with strict dominance structures choose peace over violence in some cases. My only note is that Teré’ be given the honorific Queen Mother for her service.

In other news…

The over/under on predication markets

Packin, Nizan Geslevich and Rabinovitz, Sharon. “Prediction markets as a public health threat.” Science.

Prediction markets (PMs) are exploding in popularity, but researchers warn that the “addictive design, vulnerable users, and permissive regulatory environments” that characterize these markets “are a well-established formula for population-level harm,” according to the Policy Forum section of the journal Science

PMs operated by companies like Kalshi or Polymarket “pose underappreciated threats to democratic integrity” and are linked to “addictive behaviors,” according to authors Nizan Geslevich Packin of Baruch College Zicklin School of Business and Sharon Rabinovitz of the University of Haifa. For instance, PMs can enable insider trading about classified government information and expose millions of users to the risk of addiction and major financial losses.

“A public health approach reframes PM risks as predictable outcomes of environmental design, analogous to tobacco control’s success in treating smoking as population-level exposure rather than individual vice,” the team argued in the article. 

“The window for precautionary action is closing,” the researchers emphasized. “Each week of billion-dollar PM activity…prolongs a large uncontrolled experiment on users.”

It remains to be seen whether this warning about the dangers of a wild new industry will materialize into meaningful regulatory action. Want to make a bet?

Creating new life after death

Bamford, Sandra Carol. “Spectral Connections: Anthropological Engagements with Posthumous Reproduction.” Cambridge Archaeological Journal.

Posthumous children—children born after the death of one or both parents—are popular in myth and fiction, from the Greek Dionysus to more modern characters like John Connor or Daenerys Targaryen. 

But this is also a real demographic of people that may evolve in interesting ways as reproductive technologies enable larger numbers of posthumous conceptions—in which the sperm and egg donors for an embryo may be deceased, such as the case of a boy born in 2018 whose mother and father had both died years earlier in a car crash.

In this way, “frozen sperm, eggs (or embryos) are, at one and the same time, both alive and dead,” said Sandra Bamford of the University of Toronto in a new anthropological study of the topic. “Through their frozen gametes and the potential of new kin connections in the future, the dead remain as active participants influencing the lives of the living.”

The study, which is part of a broader journal issue exploring kinship, pulls together many intriguing case studies, including the “Nuer ghost marriage” practices of Sudan, in which a deceased man can be considered the father of a kinsman’s children, or the case of William Kane, who bequeathed frozen sperm to his girlfriend, sparking a legal battle with his adult children after his death by suicide. 

In other words, the legal, ethical, and practical implications of posthumous conception are still very much in flux, raising thorny questions about when, and how, the dead can produce new life. For instance: the ambiguities over judging the consent of a deceased person over the use of their posthumous gametes; the rights of posthumously conceived children to be named heirs of estates; and the possible emotional and psychological toll on posthumously conceived children, along with their family members.  

The Rime of the Really Ancient Mariner 

Zaki, Abdallah S. and Lamb, Michael P.  “Identifying the topographic signature of early Martian oceans.” Nature. 

We’ll close, as all things should, with waves lapping on long-lost alien shores. The surface of Mars is etched with the memory of rivers, lakes, and perhaps even an expansive ocean that may have covered much of its northern hemisphere between three and four billion years ago. 

Scientists have already mapped out the rough contours of what may be an ancient Martian shoreline, but a new study throws the seas into sharper relief by identifying topographic signs of a possible coastal shelf. The team argued in their study that these shelf features may be a better indicator of a past ocean than shoreline features, based on similar observations on Earth.

Babies Born from Dead Parents Will Increase with New Tech. Are We Ready?
An illustration taken from orbiter data identifying the coastal shelf region on Mars. Image: A. Zaki

“Our results indicate that long-lived ancient oceans on presently arid planets may be best identified not only through discrete shorelines but also through…a global coastal shelf,” said researchers led by Abdallah Zaki and Michael Lamb of Caltech University. The study supports “the presence of an ancient ocean on the northern plains of Mars that was bounded by a coastal shelf.”

While this ocean dried up long ago, its topographic remnants are a reminder of a time when Mars was warm, wet, and perhaps, wriggling with life.

Thanks for reading! See you next week.

FAA Scraps Civil and Criminal Penalties for Flying Drones Near ICE Vehicles

2026-04-17 23:44:59

FAA Scraps Civil and Criminal Penalties for Flying Drones Near ICE Vehicles

On Wednesday the Federal Aviation Administration rescinded a temporary flight restriction (TFR) that created a no-fly zone within 3,000 feet of “Department of Homeland Security facilities and mobile assets.” The new restriction softened the language of the original and abandoned the threat of civil or criminal penalties but added the Department of Justice to the list of protected agencies.

A 2025 TFR restricted the presence of drones around Department of Energy and Pentagon assets. The FAA added ICE and CBP to the list of restricted agencies in January as ICE began operations in Minneapolis. The no-fly zone covered 3,000 feet around any ICE vehicle. Anyone who was caught violating it could be fined or jailed. Because ICE agents often drive through the city in unmarked vehicles it was impossible for drone operators to know if they were violating the order and local journalists who use drones to take pictures and monitor law enforcement activities were grounded.

Earlier this month, Minnesota journalist Rob Levine sued the FAA over the TFR. In a motion filed earlier this week, Levine’s lawyers argued that the FAA had violated his rights and should rescind the restrictions. Core to their argument was the unmarked vehicles which they said created a “flotilla of invisible, moving bubbles,” according to court documents. “Under any standard, the TFR’s chilling sweep violates the First Amendment as applied to the Petitioner’s use of drones in photojournalism.”

The FAA replaced the TFR this week after Levine’s lawyers filed the motion. The new advisory lessened restrictions, including dropping the language around 3,000 feet and criminal penalties, but expanded the amount of protected assets. 

“UAS operators are advised to avoid flying in proximity to: Department of War, Department of Energy, Department of Justice, and Department of Homeland Security covered mobile assets,” the new TFR said. “UAS operators who fly within this airspace are warned that…DOW, DOE, DOJ, or DHS may take action that results in the interference, disruption, seizure, damaging, or destruction of unamended [aircraft] deemed to pose a credible safety or security threat to covered mobile assets.”

Despite the threat to shoot journalist’s drones out of the sky, Levine and his lawyers see the new TFR as a victory. “This is a big win. It was heartbreaking to have my drones grounded at a time of such importance to my community, but I'm looking forward to getting back up there and getting back to my journalism as soon as possible,” Levine said in a statement provided to 404 Media.

Grayson Clary, a lawyer with Reporters Committee for Freedom of the Press who took on Levine’s case, said there is still work to do. “We're glad to see the FAA rescind its original order, which was an egregious overreach that had serious consequences for reporters nationwide. But this kind of arbitrary back-and-forth from the FAA is exactly the problem, and we intend to make clear to the D.C. Circuit that this restriction never should have been implemented in the first place,” he said.

The Destroyed Remnants of a Lost World Are Falling to Earth, Scientists Discover

2026-04-17 21:00:36

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The Destroyed Remnants of a Lost World Are Falling to Earth, Scientists Discover

The remnants of a bizarre long-lost world that fell apart before our planet was fully formed are falling to Earth in the form of meteorites, according to a new study in Earth and Planetary Science Letters

For decades, scientists have puzzled over the origin of angrites, a rare class of about 70 meteorites with unique volcanic compositions that suggest they were forged in a large ancient object with differentiated layers, including a metallic core and a magma ocean.

Scientists have long assumed that this object, the so-called angrite parent body (APB), was roughly a few hundred miles across, similar in size to the asteroid 4 Vesta. But researchers recently raised the tantalizing possibility that the APB might have been much larger, perhaps on the scale of Earth’s moon.

Now, a team led by Aaron Bell, an experimental petrologist and an assistant research professor at the University of Colorado, Boulder, has discovered “the first unequivocal evidence supporting the large angrite parent body hypothesis, which posits that the angrites are samples derived from a protoplanet that was catastrophically disrupted during the earliest evolutionary stages of the inner solar system,” according to the new study.

“It probably got destroyed in the early solar system, so [angrites] are remnants of a lost protoplanet,” Bell said in a call with 404 Media. “A few pieces broke off and are now in the asteroid belt, and a few of them have come to Earth, and we’ve picked them up.”

Angrites date back about 4.56 billion years, making them among the oldest known volcanic rocks. They belong to a class of stony “achondritic” meteorites that contain the crystalized signatures of melted rock, such as basalts, hinting that they originate in larger bodies that underwent some degree of planetary processing and layered differentiation, even if those early planetary embryos never accreted into full planets. 

“Angrites are interesting in that they don't have a known parent body,” Bell said. “It's never been definitively identified, and that's one of the mysteries.”

“There are a bunch of arguments about why angrites are so geochemically unusual,” he added. “They're kind of this oddity.” 

Most models of early planetary accretion predict that relatively small objects formed within the first few million years of the solar system, which is why the APB was assumed to be an asteroid-sized object, rather than a much larger nascent planet.

While working on a previous study, Bell became interested in an aluminum-rich angrite from Northwest Africa, known as NWA 12,774, which was classified in 2019. The meteorite is one of a handful of unusual primitive angrites that appear to have been crystallized at high pressure within the APB, indicating that it formed deep under the surface and therefore might shed light on the size of this bygone world.

“Even among angrites, there's only four or five that have these primitive compositions,” Bell said, adding that the meteorite had “off-the-charts aluminum content, which is really very unusual.”

Bell and his colleagues developed a geobarometer—a tool that calculates the pressures at which rocks and minerals formed—-that estimated it would take at least 1.7 gigapascals to account for the rock’s special properties. This pressure corresponds to an object with a minimum radius of 620 miles (1,000 kilometers), which is just under the size of Pluto. The APB may even have been as large as the Moon, which has a roughly 1000-mile radius. 

“Clearly, within the first few million years of solar system evolution, you could grow planetary embryos that were 1,000-plus kilometers” in radius, Bell said. “We're talking within three million years of the condensation of the first solids in the solar system, so it’s right at the beginning.”

The discovery suggests that the APB may have been a first-generation protoplanet that coalesced and shattered millions of years before the familiar worlds of our solar system took full shape. Judging by the strange properties of angrites, the APB was also on track to be a very different kind of world than Earth and its neighbors, had it survived the chaotic environment of its infancy. 

Angrites are “geochemically fundamentally different, and that's why people were interested in the first place—because they were odd,” Bell said. “They don't look like garden-variety

basalts you get from Mars or the Moon or Earth.”

“It's sort of this path not taken—or maybe it was, but we just have a couple pieces of it that tell us something we didn't know,” he concluded. “There were once large bodies that, maybe, didn’t look like the terrestrial planets.” 

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